1951 – Mexican chemist Luis E. Miramontes conducts the very last step of the first synthesis of norethisterone, the progestin that would later be used in one of the first three oral contraceptives.
Norethisterone (NET), also known as norethindrone, is a medication that is used in combination with estrogen or alone in hormonal contraceptives, hormone replacement therapy, and in the treatment of gynecological disorders. It is a synthetic progestogen (or a progestin) of the 19-nortestosterone group and has similar effects to those of natural progesterone, including suppression of gonadotropins, ovulation inhibition, and endometrial transformation. In addition to its progestogenic activity, NET also has weak androgenic and estrogenic effects at high dosages. In addition to NET itself, several prodrugs of NET, such as norethisterone acetate (NETA), norethisterone enanthate (NETE), and others, have been marketed and have similar effects and uses.
Luis Ernesto Miramontes Cárdenas (March 16, 1925 – September 13, 2004) was a Mexican chemist known as the co-inventor of the progestin norethisterone used in one of the first three oral contraceptives.
Miramontes was born at Tepic, Nayarit. He obtained his first Degree in chemical engineering in the Universidad Nacional Autónoma de México (UNAM). He was a founding researcher of the Institute of Chemistry of UNAM, specializing mainly in the area of Organic Chemistry. He was a professor of the Faculty of Chemistry of UNAM, Director and professor of the School of Chemistry at the Universidad Iberoamericana, and deputy Director of Research at the Mexican Institute of Petroleum (IMP). Miramontes was a member of diverse scientific societies, such as the American Chemical Society (Emeritus), the Mexican Institute of Chemical Engineers, the National Institute of Chemical and Chemical Engineers, the Chemical Society of Mexico, the American Institute of Chemical Engineers and the New York Academy of Sciences.
He died in Mexico City in 2004.
1829 – Asaph Hall, American astronomer and academic (d. 1907)
Asaph Hall III (October 15, 1829 – November 22, 1907) was an American astronomer who is most famous for having discovered the moons of Mars, Deimos and Phobos, in 1877. He determined the orbits of satellites of other planets and of double stars, the rotation of Saturn, and the mass of Mars.
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